For future tasks such as autonomous driving or Industry 4.0, ever larger amounts of data from an increasing number of sensors must be analysed in the shortest possible time using complex algorithms and artificial intelligence (AI). However, the corresponding processors must not only meet high requirements in terms of computing power, but also in terms of energy efficiency, reliability, robustness and safety, which go far beyond current possibilities. The BMBF's ZuSE projects are intended to meet the urgent need of user industries for future-proof, trustworthy processors that are tailored to their specific tasks and offer high performance.